Heike was trained and employed by Sanofi Deutschland GmbH to assist solid phase peptide and oligo nucleotide synthesis from 1997-2000. She studied biochemistry at the Goethe University of Frankfurt and gained her diploma in 2005. She worked on bacterial complex IV in the laboratory of Hartmut Michel at the Max Planck Institute of Biophysics and obtained her Ph.D. in 2009. She was a postdoctoral fellow at the group of Ulrich Brandt and started work on mitochondrial complex I of Yarrowia lipolytica at the Medical School of Frankfurt University. She started 2012 in the Structural Bioenergetics Group of Volker Zickermann with the focus on accessory subunits of mitochondrial complex I and NFS1 protein of Fe-S cluster biogenesis.