Javier was born in Manresa, Barcelona, Spain. After high school he obtained both a degree in Biology and a degree in Biochemistry at the Autonomous University of Barcelona. Following this, he completed his Master’s degree in Biochemistry at the same university. During the PhD Javier was focused on the structural and functional characterization of novel regulatory and digestive metallocarboxypeptidases. Javier completed his PhD in Biochemistry, Molecular Biology and Biomedicine in 2015 in the group of Protein Engineering and Proteomics headed by Prof. F. X. Avilés at the Institute of Biochemistry and Biomedicine (IBB-UAB). The same year, he started a postdoctoral period at the same laboratory. Afterwards, he continued his career as a postdoctoral scientist in the group of Prof. Daniel Ruiz-Molina laboratory at the Catalan Institute of Nanoscience and Nanotechnology (ICN2), developing novel Nanostructured Coordination Polymers for biomedical applications. During all these years, he performed different short-term visits to other research groups, such as the laboratory of Prof. Lloyd D. Fricker (Albert Einstein College of Medicine, New York, USA) or the laboratory of Prof. Sir Tom Blundell (Dpt. of Biochemistry, University of Cambridge, Cambridge, UK). Javier’s most significant discovery is the structural characterization of Carboxypeptidase O, a novel human digestive carboxypeptidase with particular substrate specificity against acidic residues. He joined the Dikic lab in September 2018 and he is currently working with reticulons, a group of evolutionary conserved proteins residing in the ER and involved in membrane curving. He is also trying to investigate the structure and mechanism of human DNA-dependent metalloproteases and in the discovery of new pharmacological targets for the NF-kB pathway.

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